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This compelling evidence demonstrates that mitochondria are not a direct target for GH and/or its receptor

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Mice in the GHK-Cu group had an enhanced performance on special memory tests and learning navigation tasks and demonstrated decreased neuroinflammation and axonal damage markers as compared to the placebo group

Xu et al (116) found that liraglutide could mitigate cisplatin-induced nephrotoxicity by inhibiting nuclear-cytoplasmic translocation and release of high mobility group box 1 (HMGB1), reducing inflammatory cytokine levels and HMGB1 receptor expression