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Their approach is designed to pinpoint the underlying causes of weight gainsuch as hormonal imbalances, metabolic issues, or lifestyle factorsand build a tailored plan that integrates nutrition counseling, behavior modification, physical-activity guidance, and, when appropriate, approved medications

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SAM is involved in hundreds of methylation reactions throughout the body, and the systemic effects of preserving SAM through NNMT inhibition in tissues beyond adipose tissue remain unknown