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(2) R T Dorr, R Lines, N Levine, C Brooks, et al (1996) Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study Life Sciences, 1996, Volume 58 (Issue 20), Pages 1777-84

GLP-1 use in diabetic patients also may decrease future complications of nerve damage, eye problems, gum disease, enhanced mobility, less joint pain, higher self-esteem, better sleep, possible prevention of fatal cardiovascular disease and stroke

Impaired induction of interleukin 2 and gamma interferon due to specific inhibition of dipeptidyl peptidase IV

Short-chain fatty acids, particularly butyrate and propionate, have been shown to activate receptors on enteroendocrine L-cells, triggering GLP-1 release

The drug was first approved by the FDA in 2017