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Ultimately, the goal is not rapid or extreme weight loss but, rather, safe, sustainable, and medically meaningful improvements in health and quality of life

Feng Y, Demehri FR, Xiao W, Tsai YH, Jones JC, Brindley CD, Threadgill DW, Holst JJ, Hartmann B, Barrett TA, Teitelbaum DH, Dempsey PJ (2017) Interdependency of EGF and GLP-2 signaling in attenuating mucosal atrophy in a mouse model of parenteral nutrition

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This approach is particularly helpful since both therapies can cause gastrointestinal symptoms, making it difficult to determine which medication is responsible when started simultaneously

References Meier JJ