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Preclinical and early human data suggest it may promote lipolysis, inhibit lipogenesis, and preferentially act on adipose tissue by influencing beta3 adrenergicmediated pathways and hormonesensitive lipase activity

SREBP1 activation induces stearoyl-CoA desaturase ( SCD1 ) expression, which presumably promotes the accumulation of ferroptosis-inhibitory monounsaturated fatty acids 18 though this connection awaits to be validated by lipidomics

Those who undergo GI surgery, like removal of intestines or gastric bypass, may also have difficulty with B12 absorption (4, 5)

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