Third, discuss realistic expectations: dual therapy may offer incremental weight loss gains but also carries a higher risk of side effects and requires closer follow-up than monotherapy
ONeil PM, Birkenfeld AL, McGowan B, Mosenzon O, Pedersen SD, Wharton S, Carson CG, Jepsen CH, Kabisch M, Wilding JPH (2018) Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial
What is the timeline of weight loss on semaglutide GLP-1
Nausea affects 80 to 90 percent of users but typically resolves after 3 to 5 days
It is also worth noting that a close association between the feeding state and hepatic TH metabolism has been noticed early 16 , however, the regulatory role of hepatic TH signaling in response to feeding is largely unknown