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Aging: Natural levels of glutathione decline with age, making older adults more susceptible

Age-related cognitive decline Normal aging is associated with mild cognitive impairments that are caused by various neuroanatomical changes, including alterations in brain receptors, myelin dystrophy, loss of dendritic spines, and changes in nerve transmission (146)

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Depletion of mitochondrial glutathione has been associated with increased neuronal injury and has been implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimers, Parkinsons, and multiple sclerosis

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