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Nevertheless, pharmacological levels of OXM (sufficient to activate GLP-1R and GCGR) have shown anti-obesity effects in humans, by significantly reducing appetite (108, 109) and increasing energy expenditure (110)

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Tang H, Donahoo WT, DeKosky ST, Lee YA, Kotecha P, Svensson M, Bian J, Guo J

GLP-1 treatment was safe and elicited a significant improvement in LV ejection fraction (to a mean of 39 2%) [74]

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