Offers good antioxidant protection against oxidative stress
The induction of colitis with TNBS caused elevated levels of pathological scores via activation of NF-B translocation in the colon epithelium which has been reversed by treatment with d-limonene [109]
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Pharmacological and Biological Activity of Saffron Saffron exhibits a wide range of pharmacological effects, including strong antioxidant activity, anti-inflammatory, anti-atherogenic, anti-apoptotic, antihypertensive, and hypolipidemic effects, which can reduce oxidative stress and inflammation, both of which are principal factors in central nervous system (CNS) pathologies
While glutathione is a naturally occurring antioxidant in the body, the effects of external administration via IV are not fully understood for this population