do glp 1 cause blood clots Does semaglutide clots? What the research actually shows Diabetes Foro

The rationale is elegant: because GLP-1 receptors are enriched in metabolically active brain regions, using GLP-1 as a delivery vehicle allows estrogen to be directed preferentially toward the central nervous system, potentially enhancing its neuroprotective effects while limiting systemic hormonal exposure

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You tolerate higher doses

The timeline is straightforward but its implications are anything but simple

Insulin sensitivity has changed, estrogen loss has accelerated muscle loss, and the stress response is more reactive than it was in earlier decades. A younger woman might under-eat for a period and bounce back relatively quickly