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National Library of Medicine (US), MedlinePlus

The duration of cycles and breaks depends on the specific study design

Excessively elevated IGF-1 suggests dosing higher than necessary

The regression-like pattern is seldom documented with dermoscopic monitoring, but is peculiar enough to allow a clinicopathological differential diagnosis between melanoma with regression and its main benign simulator, the so-called sclerosing nevus with pseudomelanomatous features or compound nevus with regression-like fibrosis (58, 59)