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Seek immediate care for signs of serious allergic reactions including widespread rash, facial swelling, or difficulty breathing

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These findings provide strong rationale for the ongoing Phase IIb trials investigating simplified weekly and monthly dosing regimens

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Therefore, the inclusion criteria for this NMA were based on the following PICOS model (Population, Intervention, Comparison, Outcome, and Study design): Population: Adults ( 18 years) without pre-existing neurodegenerative diseases