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Peer review Peer review information Nature thanks Evan Lien, Kyle McCommis and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

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Neurotoxins induce apoptosis in dopamine neurons: protection by N-propargylamine-1(R)- and (S)-aminoindan, rasagiline and TV1022

Clinically, this connection between mycotoxins and mast cell activation may help explain why patients with chronic mold exposure often present with a constellation of symptoms, including brain fog, fatigue, light sensitivity, anxiety, and histamine intolerance, even when traditional testing is unremarkable 13

And, surprisingly, the deficiency in LAC is even stronger in patients that dont respond to standard antidepressants. These results suggest that LAC levels may be used as an effective biomarkermeaning, a measurable physiological trait that can indicate the presence of disease (sometimes in combination with other diagnostic techniques)