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For individuals with diabetes or obesity who are benefiting from GLP-1s, increasing protein intake and incorporating strength training during rapid weight loss can help preserve muscle mass

Adherence is the most important behavior: patients must receive adequate education and support to become competent adherers

Signs of Dehydration : Symptoms including decreased urination, dark concentrated urine, persistent dizziness, rapid heartbeat, or confusion indicate significant fluid depletion requiring medical assessment

Often the metabolic improvements from weight loss persist even after medication discontinuation, at least in the short term