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What your provider may discuss during consultation

When you add alcohol, which further slows gastric motility, you create a situation where food and drink sit in your stomach for extended periods

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This also suggests that GLP-1RAs with distinct rates of receptor internalisation and lysosomal targeting might differentially regulate the kinetics of this engagement, so that slow GLP-1R internalising compounds are expected to trigger initially reduced VAPB interactions, which might however paradoxically result in prolonged VAPB engagement over time, and therefore potentially lead to sustained ER signalling, as these biased compounds are also associated with reduced lysosomal degradation from the pool of internalised receptors 18,24

Reducing inflammation may also support digestion and nutrient absorption, as discussed in How to Calm Inflammation