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The compound reliably raised GH and IGF-1, but the two largest or longest trials the Alzheimers study and the two-year healthy-elderly study failed to show benefit on the outcomes that actually matter (cognition/function and strength/function, respectively)

Be cautious if you have cancer

Khnen P, Krude H, Biebermann H

Comparison With Bariatric Surgery and Endoscopic Therapies Anti-obesity medications, endoscopic therapies, and bariatric surgery differ in invasiveness, reversibility, cost, durability, risk profile, and expected magnitude of weight loss