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Perhaps most significantly are the big increases in assay sensitivity and the widening of the dynamic range accomplished by using alternatives to the traditional colorimetric detection and miniaturization

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As an aside if you are interested in knowing your risk for metabolic disease, have fasting insulin levels drawn, check your fasting glucose level, then determine your HOMA-IR score, check your homocysteine, uric acid, hs-CRP, triglycerides, and get a DEXA scan for visceral fat and lean mass determination