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Research must study spirulina safety as a long-term treatment and its interactions with pharmaceutical medicines before it can be adopted as a safe detoxification solution.[2] Spirulina demonstrates the best security-based features for toxic substance clearance enabling the support of liver health

In the long-term, angiogenesis occurring predominantly in the subacute stage allows blood flow restoration to previously ischemic areas and reduces BBB permeability by contributing to the reduction of brain-derived factors that increase BBB permeability (204)

This ultimately promotes healthy functioning of the intestinal epithelium which is required for the effective orchestration of vital processes in the gut, including locomotion, digestion, absorption, as well as modulation of neuroendocrine and immune pathways (Peterson and Artis 2014

26:961-970 [PubMed: 38073422] 376

9,12 The search for effective treatments in HFpEF has driven considerable research, particularly focusing on novel therapeutic targets