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Likewise, in the SURPASS-3 trial, all three doses of TZP caused a significant decrease in mean SBP from baseline (from 4.9 to 6.6 mmHg)

These studies raised the possibility that NTBC is associated with neuropsychological deficits that previously had not manifested in HT-1 patients

However, these patients in this study were not randomized to treatment vs

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Your provider must assess for contraindications (medullary thyroid cancer history, severe retinopathy) and oversee dose escalation