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Functional instability involves neuromuscular deficits including impaired proprioception, delayed muscle reaction times, and poor motor control that persist even when mechanical structures appear intact

In our summary, we found that the types of disorders treated in the pharmacodynamic studies of these drugs were all psychiatric

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The Lancet (2021) This Phase 2 dose-finding trial randomized adults with overweight or obesity without diabetes to cagrilintide at doses from 0.3 to 4.5 mg weekly, placebo, or liraglutide 3.0 mg daily as an active comparator across 57 sites in 10 countries