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5 Mechanisms by which metformin acts through regulation of the gut microbiota 5.1 Acts by stabilizing the mucosal barrier of the GI tract The GI mucosal barrier with important physiological roles is a three-dimensional protective structure consisting of mechanical, chemical, immune and biological barriers

When two groups were compared, a two-tailed unpaired Students t -test was applied

or (b) deuterated solvent (D 2 O, PBS or carbonate)

doi:10.1210/mend.16.4.0798

The fraction of surplus calories that end up as muscle versus fat is called nutrient partitioning, and it is heavily influenced by insulin sensitivity