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Cutaneous delivery utilizing nanocarriers allows for targeted drug delivery to specific psoriatic lesions while minimizing systemic side effects, offering substantial benefits in managing inflammatory skin conditions, including acne, inflammation, infections, and wound healing (24, 27)

This method may help support nerve function more effectively, particularly where deficiency or functional low levels are suspected

Zgair A, Dawood Y, Ibrahem SM, Back H, Kagan L, Gershkovich P, Lee JB

Common side effects include pain, redness, or swelling at the injection site, which typically resolve within 2448 hours

The following sections organize the mechanistic rationale into a structured framework to support experimental planning and outcome measurement