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10.1038/s41380-021-01334-4 105 KleschevnikovA

Retatrutide's GLP-1 and GIP receptor activation directly enhances insulin secretion and glucose disposal

[1] [2] This mechanism leads to reduced hunger, increased feelings of fullness, and decreased food cravings, making it easier for patients to adhere to a reduced-calorie diet

Zhang X, Yin M, Zhang LJ

Quick Answer: Semaglutide does not directly provide energy but may improve energy levels indirectly through better blood sugar control, weight loss, and improved metabolic health over several months of treatment