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2018;27(6):1281e12931287

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4 Cellular mechanisms regulated by ChaC1 CHAC1 catalyzes the breakdown of GSH into 5-oxo-proline and Cys-Gly, thereby reducing intracellular GSH levels

10.1016/j.ejphar.2019.01.064 [DOI] [PubMed] [Google Scholar] Wang N., Xue P., Li Z., Li Y

17 In addition to these findings, the SUSTAIN-6 trial also showed that semaglutide can offer a significant reduction in the risk of new or worsening nephropathy including persistent macroalbuminuria, increase in serum creatinine or the need of renal replacement therapy