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Melatonin reprograms the effector state of activated ILC2s To further dissect the effects we had observed, we isolated aILC2s from IL-33 challenged BALB/c mice ( Supplementary Figures 2 ) and performed bulk RNA sequencing, comparing the transcriptome of vehicle and melatonin treated cells ( Figure 5A )

doi: 10.1016/j.neuroscience.2015.09.070 6

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This contributes to both its healing properties (maintaining blood supply to injured tissue) and its protective effects against various forms of organ damage