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Inflammation Inflammatory 'pathogens' stimulate the release of histamine and cause leaky gut allowing histamine into our blood stream causing systemic symptoms

A major real-world study published in early 2026 led by researchers at Johns Hopkins Bloomberg School of Public Health and analysing electronic health records from approximately 175,000 people with T1D in the US found that those taking GLP-1 drugs had a roughly 15% lower five-year risk of major cardiovascular events and a 19% lower risk of end-stage kidney disease, without any increase in hospitalisation for DKA or severe hypoglycemia

Prion diseases share characteristics of prion-like neurodegenerative diseases in terms of the involvement of proteins (-synuclein, amyloid , and tau) forming amyloid deposits [266]