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The corresponding author (Malay Kumar Adak) gratefully acknowledges the DST PURSE program of the University of Kalyani [Award No.: SR/PURSE Phase 2/37(G)]

Spironolactone is FDA-approved to treat: Heart failure Hypertension (high blood pressure) Edema (swelling caused by fluid retention) due to cirrhosis or kidney disease Hyperaldosteronism (too much aldosterone in the body) Spironolactone also has a number of off-label uses

Its commonly used due to its stability and affordability

Samples were classified into molecular subtypes using the Random Forest (RF) method available in the R package of the CMS classifier (v100, In order to normalise the data of these 12 patients, we used a piggyback cohort of 196 primary tumour samples of colorectal cancer with varying disease Stage IIV