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J Biosci Bioeng 2019

It has a specified dose form, excipients, release characteristics, manufacturing quality system, label, storage requirements, and clinical instructions

MM/PBSA (Molecular Mechanics/Poisson-Boltzmann Surface Area) calculates the free energy difference between the ligand and the protein-ligand complex in various states, which helps evaluate the binding affinity of a ligand to a protein

If clinical data from other delivery route studies prove encouraging, intranasal formulations could receive more attention and investment

If peptides will be used immediately or within the next few days, weeks, or months, short-term refrigeration below 4C (39F) is generally acceptable