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The enzyme glutathione reductase can convert GSSG back to GSH using NADPH as a cofactor, which is an important part of cellular defenses against oxidative stress

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The therapeutic benefits of glycine that matter most for semaglutide users include muscle preservation during caloric deficit, improved sleep quality, enhanced glutathione production for antioxidant protection, anti-inflammatory effects, support for collagen synthesis, and improved insulin sensitivity

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