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Cell Host & Microbe DOI:10.1016/j.chom.2026.05.003 Abstract Microbiota-driven gutbrain signaling underlies antidepressant effects of a GLP-1 analog Despite widespread clinical use of glucagon-like peptide-1 receptor (GLP-1R) agonists for metabolic disease, their neuropsychiatric effects remain poorly understood and controversial

In the worst-case scenario, you could also be risking unmonitored side effects or drug interactions