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Any stomach disorders, or conditions like pernicious anemia where Intrinsic Factor is lacking, can prevent B12 absorption, as can intestinal inflammation such as Crohns disease if a damaged terminal ileum cannot take up vitamin B12

Homeostatic plasticity and NMDA receptor trafficking

doi: 10.1038/ejcn.2013.90 48 NymoSCoutinhoSRJrgensenJRehfeldJFTrubyHKulsengBet al

Differential effects of intra-ventral tegmental area ghrelin and glucagon-like peptide-1 on the stimulatory action of D-amphetamine and cocaine-induced ethanol intake in male Sprague Dawley rats