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Semaglutide is considered safe for long-term use in managing weight when used as directed and under the care of a knowledgeable provider

Obesity can cause a host of health problems, including various cancers, coronary heart disease, high blood pressure, stroke, Type 2 diabetes, sleep apnea and more

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When semaglutide and lifestyle interventions were discontinued on the individuals from the STEP 1 trial, they regained the majority of their weight lost