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65 Thus, gain of detrimental effects is likely to be context-dependent and unique to specific situations and effective treatment will require understanding the distinctive situations under which they arise

This involves giving large doses of B12 injections, possibly every day or week, for a certain time

Organ-on-a-chip models Over the past decade, the development of a novel technique known as organ-on-a-chip (OOAC) has gained great popularity [262, 263]

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10.1172/jci.insight.93382 Summary Keywords glucagon-like peptide-1 receptor agonists, ocular diseases, glaucoma, diabetic retinopathy, mechanism Citation Xie Z, Yang Z, Tian D and Chen Y (2025) Unlocking the potential of GLP-1 receptor agonists in ocular therapeutics: from molecular pathways to clinical impact