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67 Regarding the effects of increased antidiabetic action and decreased body weight by dual stimulation of GIP and GLP-1R, more than either GIP or GLP-1 alone, one of the reasons that might be postulated for this synergism is that GIP signals mediate insulinotropic and glucagonotropic effects through the brain or fat

The analysis revealed that variants in the 'GLP1R' gene, which codes for the GLP-1 receptor, were associated with the drug's effectiveness

This may vary among individuals

Nutritional Changes: Eating significantly less food can alter your intake of vital nutrients, which is especially important if you take certain blood thinners like warfarin

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