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Lack of Large-Scale Studies: Few comprehensive studies exist, especially for individuals without a nutrient deficiency

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Mushrooms and Health Summit Proceedings, The Journal of Nutrition, Volume 144, Issue 7, July 2014, Pages 1128S1136S, Institute of Health, Office of Dietary Supplements Selenium Fact Sheet for Health Professionals, accessed April 11, 2019 Feng,Lei, Cheah,Irwin Kee-Mun, Ng, Maise Mei-Xi et.al