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To view digital features for this article, go to Introduction Some scientists have proposed that the skin cannot be treated fully from the inside to the outside owing to the anatomy and physiology of dermal structures [1]

The functional intracellular status of micronutrients involved in cell metabolism is evaluated by manipulation of the individual micronutrients in the media, followed by mitogenic stimulation and measurement of DNA synthesis

So IVs may do the justice for you, but may not be enough

Dermatologa esttica : Leyden et al

On May 4, the publisher issued a retraction notice stating: Concerns were raised about the data in this paper post-publication