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Like Hashimotos disease, its considered an autoimmune condition

Multiple epigenetic clocks were evaluated: first-generation (Horvath, Hannum), second-generation (PhenoAge, GrimAge, including principal-component GrimAge (PCGrimAge), a mortality-linked estimator), the third-generation DunedinPACE, which indexes the pace of aging, and OMICmAge (multi-omic methylation age)

Key genetic markers in the GLP1R and GIPR genes influence receptor sensitivity and appetite signaling, meaning some individuals naturally see faster results than others taking the same dose

People using GLP1s without clinical oversight often miss the education piece around protein intake and resistance training and thats exactly where the greater leanmass loss shows up

Short answer: Possibly