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Moderate ROS can activate PI3K/AKT and MAPK/ERK pathways to upregulate VEGF expression and VEGFR-2 phosphorylation, which further promote endothelial proliferation, migration, and vasculogenesis (71)

Accelerated Wound Healing Promotes faster tissue repair and wound closure through enhanced fibroblast activity, angiogenesis, and extracellular matrix remodelingbeneficial for surgical recovery and injury healing

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We found that the density of Ki67+ cells is significantly reduced in the subgranular zone of DG-NR1KO mice compared with control ( p = 0.023, t (11) = 2.641, n = 6 control and 7 DG-NR1KO mice, independent-sample t test, two-tailed