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The ability of curcumin to down-regulate the expression of fibronectin, one of the ECM proteins, which is overexpressed in leiomyoma as compared to normal myometrium, has also been documented ( Camellia sinensis (L.) Kuntze [Theaceae] (Green Tea) in Uterine Fibroids A randomized controlled trial reported on the effect of green tea extract [45% epigallocatechin gallate (EGCG)] in women with symptomatic UF showed a significant reduction in the fibroid volume as compared to the placebo group after taking 800 mg of green tea extract for the duration of 4 months