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Diabetes mellitus and its degenerative complications: a prospective study of 4,400 patients observed between 1947 and 1973
A., Trickett, A
Introduction Amodiaquine is a potent anti-malaria drug, however, rare but life-threatening idiosyncratic hepatotoxicity (1/15,500 patients) and agranulocytosis (1/2000 patients) have restricted its therapeutic use (Olliaro and Mussano, 2003
The number of potential disease targets obtained through searching the DisGeNET, Pharm Gkb, OMIM, and DrugBank disease databases was 988, 326, 188, and 32, respectively
Hold: Keep the dose constant across all 4 weeks rather than titrating
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