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Expanded access (sometimes called "compassionate use") is an FDA pathway that lets patients with serious conditions receive an investigational drug outside a clinical trial when no comparable approved option exists

The BELIEVE Phase 2b trial highlighted superior results with this combination, demonstrating a 22.1% weight reduction, surpassing the outcomes of both treatments administered separately

Both lifestyle modifications and medical interventions play important roles

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Meanwhile, metformin remains a cornerstone therapy, particularly for improving insulin sensitivity and regulating menstrual cycles