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Further, while the mimetics include certain N-acyl groups as specified in Table 1 (Family 1), in the practice of various embodiments of the invention other N-acyl groups or substituted or unsubstituted phenyl groups may be used at i

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Unlike approved drugs, they havent undergone the rigorous testing required to understand their safety profile in humans

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High-dose NAC was a priori defined as a daily dose greater than 1200 mg or a single peri-procedural dose greater than 600 mg, peri-procedural being defined as immediately or within 4 hours of planned contrast agent exposure