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Oral semaglutide (Rybelsus) formulations currently available include 3 mg, 7 mg and 14 mg tablets, with higher-dose tablets 25 mg and 50 mg are under investigation in OASIS trials for improved weight-loss efficacy[16]

Eli Lilly is already looking at tirzepatide for obstructive sleep apnoea and metabolic dysfunction-associated steatohepatitis in ongoing phase II and III trials, that are expected to bring deeper understanding of where the greatest benefits may be for GLP-1s over the next five years

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