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9 The STEP 8 trial directly compared once-weekly semaglutide, 2.4 mg, vs once-daily liraglutide, 3.0 mg, for weight management in adults with overweight or obesity to rigorously assess differences in efficacy and adverse event (AE) profiles

People carrying either of the two prevalent gain-of-function MC4R variants (V103I and I251L

"Of course, when you ride a wave, and you have to share it with lots of people you don't have that much space to surf." "The question is, do you just double down on that that's the bubble or do you actually say 'we're going to try and find the next scientific wave'?"

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