There's no evidence that you build tolerance to BPC-157, but cycling off periodically is still considered good practice
Joint, Tendon, and Gut: BPC-157 BPC-157 is the peptide patients ask about most for inflammation
Lifestyle factors matter
10.1074/jbc.M111.253039 Summary Keywords stable gastric pentadecapeptide BPC 157, fistula, bleeding disorder, concept practical applicability, wound healing Citation Seiwerth S, Milavic M, Vukojevic J, Gojkovic S, Krezic I, Vuletic LB, Pavlov KH, Petrovic A, Sikiric S, Vranes H, Prtoric A, Zizek H, Durasin T, Dobric I, Staresinic M, Strbe S, Knezevic M, Sola M, Kokot A, Sever M, Lovric E, Skrtic A, Blagaic AB and Sikiric P (2021) Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
Moreover, during CRPC progression, FOXA1 frequently undergoes somatic alterations, some of which can advance the progression of CaP and activate a CaP-specific AR-driven oncogenic transcriptional program [70, 71]