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Semaglutide is an FDA-approved medication originally developed to treat type 2 diabetes, but it has gained recognition for its effectiveness in weight management

Study 8, a 72-week trial in 1,407 patients with obesity, tested a 7.2 mg dosage against 2.4 mg and placebo and is the basis for the higher labeled maximum now in the Wegovy label

Recent multi-segmental magnetic resonance imaging study comparing patients with T2DM and healthy controls have found that patient T2DM group had 40% larger small bowel volume, less small bowel motility postprandially and there were positive associations between small bowel motility and constipation scores ( Conclusion This study identifies distinct expression patterns and functional effects of GLP-1 and GIP in jejunal muscle from obese individuals with and without T2DM

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This role extends beyond dispensing into active risk management