Hepatoprotective effect of 2-O-galloylhyperin against oxidative stress-induced liver damage through induction of Nrf2/ARE-mediated antioxidant pathway
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Genetic variation in GLP-1 receptor structure (rs6923761), GLP-dependent insulinotropic polypeptide signaling (GIPR rs1800437), and metabolic regulators like FTO (rs9939609) influence both drug efficacy and side effect severity
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Unlike the full-length growth hormone, AOD9604 retains the lipolytic (fat-mobilizing) and anti-lipogenic (fat-inhibiting) properties of hGH, while importantly lacking its proliferative effects (e.g., on glucose levels, IGF-1 production, or cell proliferation)