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Typically, patients with significant baseline weight, moderate-to-severe insulin resistance, or established type 2 diabetes who have tolerated escalation well and whose providers identify additional metabolic benefit

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Practical injection tips Several practices improve injection experience and consistency: Allow refrigerated solution to warm slightly before injection to reduce discomfort Clean injection sites with alcohol and allow to dry completely Inject slowly rather than rapidly pushing the plunger Keep a log of injection sites to ensure proper rotation If using acetic acid reconstitution, dilute with BAC water immediately before injection Because IGF-1 can lower blood sugar, having a small carbohydrate source available after injection helps prevent hypoglycemic symptoms

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