Mice studies do show that they live longer when given supplemental melatonin over the course of their lives, starting in adulthood.[ref][ref][ref][ref] Animal studies also show that melatonin supplementation (beginning in middle to old age) prevents the decrease in bone mass associated with aging.[ref] It also increases mitochondrial function.[ref] Melatonin is necessary to reap the benefits of exercise when aging.[ref] Supplemental melatonin also doubles insulin sensitivity in older animals.[ref] We dont do human studies on chronic calorie restriction to extend lifespan nor have there been long-term studies in humans on supplemental melatonin for fifty-plus years to know the effect
That can lead to malnourishment if the person isnt eating enough while doing hard physical activity like, say, training for a half-marathon
Hence we can experience bloating, belching, flatulence, abdominal pain, nausea, constipation, diarrhoea, malabsorption, weight loss, and malnutrition
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Bariatric Surgery: Which Is More Long-Term
