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Beyond triple agonism, researchers are exploring other combination approaches, including incretin plus amylin agonism or incretin plus FGF21 activation

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While its not a miracle cure and wont work for everyone, it has shown promising results in clinical trials

We and others have demonstrated that GLP-1R signalling elevated ATP levels 38, 39 , strengthening the hypothesis that the incretin hormone may promote -cell function through regulation of energy metabolism, especially considering the central role that ATP generation and an increase in ATP/ADP ratio play during GSIS